O presente artigo tem como objetivo analisar as fragilidades ambientais diante das intervenções humanas na bacia do córrego do Bispo, uma área bastante representativa do processo de ocupação desordenado na Serra da Cantareira. Como fundamento teórico-metodológico, adotou-se a proposta de ROSS (1994) - Análise empírica da fragilidade dos ambientes naturais e antropizados, baseada nos conceitos de Unidades Ecodinâmicas de TRICART (1977). O diagnóstico das fragilidades ambientais, sintetizado no Mapa das Unidades Ecodinâmicas de Instabilidade Potencial e Emergente, baseou-se na correlação de quatro fatores de análise: o relevo, o solo, a cobertura vegetal/uso da terra e o regime pluviométrico.Human activities, in recent decades, have had enormous impact on natural landscapes, and having as consequences natural disasters events, that culminate with natural, social and economic losses. Against this background, this research aims to analyze the society performance as a geomorphological agent, i.e. how urbanization will affect / accelerate geomorphological processes in a particular area. Therefore, the Massif Bonilha and its surroundings, in the Metropolitan Region of São Paulo, was adopted as the study area. In order to achieve the goal were made literature and mapping surveys, preparation of cartographic material and conducting field work conference for the products manufactured. Maps of the urban development and susceptibility to landslides in the study area were prepared, showing that areas with steep slopes and occupied have susceptibility installed. The results reaffirm the environmental problem of worsening natural disasters in areas prone to natural hazards occupied by irregular housing and auto self construction.