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Impact of semi-annual albendazole on lymphatic filariasis and soil-transmitted helminth infection : parasitological assessment after 14 rounds of community treatment

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dc.creator /Pion, Sébastien
dc.creator /Chesnais, Cédric
dc.creator Weil, G. J.
dc.creator Louya, F.
dc.creator /Boussinesq, Michel
dc.creator Missamou, F.
dc.date 2022
dc.date.accessioned 2022-04-27T17:37:56Z
dc.date.available 2022-04-27T17:37:56Z
dc.identifier https://www.documentation.ird.fr/hor/fdi:010084346
dc.identifier oai:ird.fr:fdi:010084346
dc.identifier Pion Sébastien, Chesnais Cédric, Weil G. J., Louya F., Boussinesq Michel, Missamou F.. Impact of semi-annual albendazole on lymphatic filariasis and soil-transmitted helminth infection : parasitological assessment after 14 rounds of community treatment. 2022, 106 (2), p. 729-731
dc.identifier.uri http://biblioteca-repositorio.clacso.edu.ar/handle/CLACSO/169177
dc.description Between October 2012 and October 2015, we conducted a community trial to assess the impact of semi-annual (twice yearly) community treatment with albendazole on lymphatic filariasis in Seke Pembe, a village in the Republic of the Congo. Semi-annual community treatment with albendazole has been continued in the community since October 2015. We conducted an additional parasitological assessment survey in October 2019, 6 months after the 14th round of semi-annual treatment. Between October 2012 and October 2015, Wuchereria bancrofti antigenemia and microfilaremia rates in the community had decreased from 17.3% to 4.7% and from 5.3% to 0.3%, respectively. In October 2019, the antigenemia rate had decreased further to 2.8% (19 of 687). No microfilariae were found in night blood smears from persons with circulating filarial antigenemia (0 of 16), suggesting that W. bancrofti transmission has been interrupted in Seke Pembe. Semi-annual albendazole treatments also reduced significantly infection rates with soil transmitted helminths.
dc.language EN
dc.title Impact of semi-annual albendazole on lymphatic filariasis and soil-transmitted helminth infection : parasitological assessment after 14 rounds of community treatment
dc.type text
dc.coverage CONGO


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