High SARS-CoV-2 prevalence among healthcare workers in Cochabamba, Bolivia

Villarroel, P. M. S.; Soto, M. D. C.; Undurraga, V.; Sanz, H.; Jaldin, A. M.; Ninove, L.; Nurtop, E.; Pezzi, L.; Ali, S. M.; Amroun, A.; /Seston, Morgan; de Lamballerie, X.

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dc.creator	Villarroel, P. M. S.
dc.creator	Soto, M. D. C.
dc.creator	Undurraga, V.
dc.creator	Sanz, H.
dc.creator	Jaldin, A. M.
dc.creator	Ninove, L.
dc.creator	Nurtop, E.
dc.creator	Pezzi, L.
dc.creator	Ali, S. M.
dc.creator	Amroun, A.
dc.creator	/Seston, Morgan
dc.creator	de Lamballerie, X.
dc.date	2022
dc.date.accessioned	2022-04-27T17:37:55Z
dc.date.available	2022-04-27T17:37:55Z
dc.identifier	https://www.documentation.ird.fr/hor/fdi:010084360
dc.identifier	oai:ird.fr:fdi:010084360
dc.identifier	Villarroel P. M. S., Soto M. D. C., Undurraga V., Sanz H., Jaldin A. M., Ninove L., Nurtop E., Pezzi L., Ali S. M., Amroun A., Seston Morgan, de Lamballerie X.. High SARS-CoV-2 prevalence among healthcare workers in Cochabamba, Bolivia. 2022, 14 (2), p. 232 [10 p.]
dc.identifier.uri	http://biblioteca-repositorio.clacso.edu.ar/handle/CLACSO/169163
dc.description	Healthcare workers (HCWs) are at increased risk of SARS-CoV-2 infection. The aim of the study was to estimate the SARS-CoV-2 seroprevalence among HCWs in Cochabamba, Bolivia and to determine the potential risk factors. In January 2021, a cross-sectional SARS-CoV-2 seroprevalence study was conducted in 783 volunteer clinical and non-clinical HCWs in tertiary care facilities. It was based on IgG detection using ELISA, chemiluminiscence, and seroneutralisation tests from dried blood spots. Analysis revealed a high seroprevalence (43.4%) of SARS-CoV-2 IgG antibodies. The combination of anosmia and ageusia (OR: 68.11; 95%-CI 24.83-186.80) was predictive of seropositivity. Belonging to the cleaning staff (OR: 1.94; 95%-CI 1.09-3.45), having more than two children in the same house (OR: 1.74; 95%-CI 1.12-2.71), and having been in contact with a close relative with COVID-19 (OR: 3.53; 95%-CI 2.24-5.58) were identified as risk factors for seropositivity in a multivariate analysis. A total of 47.5% of participants had received medication for COVID-19 treatment or prevention, and only ~50% of symptomatic subjects accessed PCR or antigenic testing. This study confirms a massive SARS-CoV-2 attack rate among HCWs in Cochabamba by the end of January 2021. The main risk factors identified are having a low-skilled job, living with children, and having been in contact with an infected relative in the household.
dc.language	EN
dc.subject	seroprevalence
dc.subject	SARS-CoV-2
dc.subject	healthcare workers
dc.subject	Bolivia
dc.title	High SARS-CoV-2 prevalence among healthcare workers in Cochabamba, Bolivia
dc.type	text
dc.coverage	BOLIVIE
dc.coverage	COCHABAMBA