Las historias uruguayas tratadas en este ensayo son las de la “Virgen de los Treinta y Tres Orientales” y de la primera Beata de Uruguay, Madre Maria Francesca Rubatto: una laica italiana, piamontesa, consagrada, dedicada pienamente a trabajar en su volontariato a favor de los pobres de Montevideo. Su amistad con el médico sardo Juan Antonio Crispo Brandis, que emigrò a Uruguay en el año 1872, la ayudará a resolver las iniciales dificultades que se le presentaron en el Hospital Italiano de Montevideo, donde trabajaba Crispo Brandis, sino en su trabajo social que la madre realizaba en los barrios más pobres cercanos a la capital.This essay deals with the Uruguayan stories of the “Virgin of the Thirty-Three” and the first Beatified Uruguayan woman, Mother Maria Francesca Rubatto, an Italian laywoman, from Piedmont, consecrated and fully devoted to work in her volontariato to help the poorest people of Montevideo. He was also a friend of the Sardinian physician, Juan Antonio Crispo Brandis, who migrated to Uruguay in the year 1872 a nd initially supported her to face the difficulties arisen in the Italian Hospital of Montevideo, where Crispo Brandis used to work, and assisted her in the social work she carried out throughout the poorest neighbourhoods near to the capital city